Fig. 1

Microglial depletion and repopulation following tamoxifen (TAM) administration. a Scheme of the genetic design. b Scheme of the repopulation study. c Representative Iba-1 staining slides for microglia in the striatum level at each time point. Scale bar indicates 200 μm in the upper column and 50 μm in the lower column. The square in the upper column indicates higher magnification in the lower column. d The Iba-1⁺ cell density in the striatum level and hippocampus level in male mice. e The Iba-1⁺ cell density in the hippocampus level in female mice