Fig. 2

Offspring body weight in adulthood. Average body weight for PND90 offspring per sex and maternal diet condition ± SEM. n = 24 animals in total were used per diet group and per sex (n = 24 CHD females; n = 24 HFD females; n = 24 CHD males; n = 24 HFD males). n = 1 female and n = 1 male offspring were sampled per litter across four challenge conditions (baseline diet (n = 6), diet + CORT (n = 6), diet + LPS (n = 6), and diet + CORT + LPS (n = 6). All CHD female and male offspring originated from n = 6 dams that were on a CHD diet and all HFD female and male offspring originated from n = 6 dams that were on a HFD diet. CHD = control house-chow diet, HFD = high-fat diet. *p < 0.0001 for main effect of diet and main effect of sex