Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study

Fig. 6

Quantitative fluorescent in situ hybridization (FISH) of the gene transcript of PTGS2 (the gene that encodes COX-2) after a single lipopolysaccharide (LPS) injection in monkey 1. In contrast to healthy control, marked PTGS2 transcript was detected in prefrontal cortex (PFC) and putamen, both ipsi- and contralaterally to the injection site in putamen. PTGS2 transcript was primarily colocalized (~ 75%) in neurons in cortex and putamen

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094