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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Spinal cord NLRP1 inflammasome contributes to dry skin induced chronic itch in mice

Fig. 1

AEW treatment activates spinal cord NLRP1 inflammasome in mice. a The scheme of experiments with AEW-induced dry skin itch. b Photographs of shaved mouse back/neck after AEW treatment. c Statistical results showing AEW treatment increased the number of spontaneous scratches, n = 10. df Representative immunoreactive bands and statistical results showing AEW treatment increased the protein expression of NLRP1, ASC and caspase-1 in the spinal cord, n = 6. gi Statistical results showing AEW treatment increased the mRNA levels of NLRP1, ASC and caspase-1 in the spinal cord, n = 6, Data are expressed as means ± SEM, *P< 0.05 and **P < 0.01 vs control group.

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