Fig. 1

CD11b mediates P + M-induced LC/NE neurodegeneration in mice. a CD11b was immunostained with anti-CD11b antibody in the brainstem of P + M-treated mice, and the density of CD11b immunoreactivity was quantified. b The expressions of CD11b in the brainstem were determined by Western blot, and the band density of blots was quantified. c LC/ NE neurons were immunostained with anti-TH antibody in P + M-treated WT and CD11b KO mice, and the representative images were shown. d The number of THir neurons in the LC was counted. n = 6 and 8 for WT and CD11b KO group, respectively. **p < 0.01. Scale bar = 100 μm