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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson’s disease model

Fig. 7

Glybenclamide mitigates P + M-induced oxidative stress in mice. a The production of ROS was determined by using DC-FDA probe. n = 4. b, c The expressions of 4-HNE were determined in the brainstem of P + M-treated mice with or without glybenclamide by Western blot, and the density of blots was quantified. d, e The expressions of NOX2 subunits (gp91phox and p47phox) and iNOS were determined in the brainstem of P + M-treated mice with or without glybenclamide by Western blot using specific antibodies, and the density of blots was quantified. n = 6 for each group. *p < 0.05. **p < 0.01

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