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Table 10 Demographic and CSF findings in MOG-EM stratified according to OCB status

From: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

 

OCB+ patients (at least once positive)

OCB– patients (never positive)

Sex (m:f)

Patients

1:1.5

1:1.5

 

Origin (non-Caucasion:Caucasian)

Patients

1:14

1:11

 

Median age at first OCB+ LP

Years

34

38

 

Median disease duration at first OCB+ LP

Months

0 (0-16)

0 (0-489)

 
  

OCB+ all samples

OCB− all samples

 

Pleocytosis

Samples

13/19 (68.4%)

57/128 (44.5%)

p = n.s.

WCC

Samples

14 (0-151)

4 (0-463)

p = n.s.

WCC > 150

Samples

1/18 (5.6%)

9/128 (7%)

p = n.s.

Granulocytes

Samples

3/10 (30%)

26/62 (41.9%)

p = n.s.

QAlb > Qlim(Alb)

Samples

11/17 (64.7%)

51/117 (43.6%)

p = n.s.

CSF TP elevated

Samples

8/18 (44.4%)

50/122 (41%)

p = n.s.

CSF l-lactate elevated

Samples

3/12 (25%)

22/91 (24.2%)

p = n.s.

Treated at the time of OCB testing

Samples

10/20 (50%)

48/131 (36.6%)

p = n.s.

Time since attack onset

Days

14

12.5

 
  1. IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein; WCC white cell count