Table 4 Immunoglobulin class response patterns in MOG-IgG-positive EM
Units | Total | Attack | Remission | Acute MY subgroup | Acute ON subgroup | Acute BRAIN subgroup | |
|---|---|---|---|---|---|---|---|
a. Based on QIg > Qlim(Ig) | |||||||
3-class reaction | Samples | 1/107 (0.9%) | 1/81 (1.2%) | 0/19 (0%) | 1/38 (2.6%) | 0/36 (0%) | 0/6 (0%) |
2-class reaction | Samples | 5/107 (4.7%) | 4/81 (4.9%) | 1/19 (5.3%) | 2/38 (5.3%) | 2/36 (5.6%) | 0/6 (0%) |
IgG + IgM | Samples | 3/107 (2.8%) | 3/81 (3.7%) | 0/19 (0%) | |||
IgG + IgA | Samples | 2/107 (1.9%) | 1/81 (1.2%) | 1/19 (5.3%) | |||
IgM + IgA | Samples | 0/107 (0%) | 0/81 (0%) | 0/19 (0%) | |||
1-class reaction | Samples | 15/107 (14%) | 15/81 (18.5%) | 0/19 (0%) | 10/38 (26.3%) | 3/36 (8.3%) | 2/6 (33.3%) |
Only IgG | Samples | 4/107 (3.7%) | 4/81 (4.9%) | 0/19 (0%) | |||
Only IgM | Samples | 9/107 (8.4%) | 9/81 (11.1%) | 0/19 (0%) | |||
Only IgA | Samples | 2/107 (1.9%) | 2/81 (2.5%) | 0/19 (0%) | |||
b. Based on Ig-IF > 10% | |||||||
3-class reaction# | Samples | 1/107 (0.9%) | 1/81 (1.2%) | 0/19 (0%) | 1/38 (2.6%) | 0/36 (0%) | 0/6 (0%) |
2-class reaction§ | Samples | 1/107 (0.9%) | 1/81 (1.2%) | 0/19 (0%) | 1/38 (2.6%) | 0/36 (0%) | 0/6 (0%) |
IgG + IgM | Samples | 1/107 (0.9%) | 1/81 (1.2%) | 0/19 (0%) | |||
IgG + IgA | Samples | 0/107 (0%) | 0/81 (0%) | 0/19 (0%) | |||
IgM + IgA | Samples | 0/107 (0%) | 0/81 (0%) | 0/19 (0%) | |||
1-class reaction | Samples | 9/107 (8.4%) | 8/81 (9.9%) | 1/19 (5.3%) | 3/38 (7.9%) | 4/36 (11.1%) | 1/6 (16.7%) |
Only IgG | Samples | 3/107 (2.8%) | 3/81 (3.7%) | 0/19 (0%) | |||
Only IgM | Samples | 4/107 (3.7%) | 4/81 (4.9%) | 0/19 (0%) | |||
Only IgA | Samples | 2/107 (1.9%) | 1/81 (1.2%) | 1/19 (5.3%) | |||