|
Units
|
Severe attacks
|
Mild/moderate attacks
|
p value
|
---|
WCC, all
|
Cells/μl
|
43.3 (0-410; 35)
|
7 (0-463;83)
|
0.0005
|
WCC, elevated
|
Samples
|
28/35 (80%)
|
44/83 (53%)
|
0.007
|
WCC, if elevated
|
Cells/μl
|
47 (6-410; 28)
|
24 (6-463;44)
|
n.s.
|
Neutrophils, all LPs
|
Samples
|
8/17 (47.1%)
|
18/40 (45%)
|
n.s.
|
OCB, pattern 2 or 3
|
Samples
|
5/32 (15.6%)
|
7/78 (9%)
|
n.s.
|
Link index
|
Samples
|
5/30 (16.7%)
|
4/68 (5.9%)
|
n.s.
|
QIgG, all
|
Ratio
|
4.2 (0.9-23.6; 30)
|
3.2 (1.1-14.1; 69)
|
0.012
|
QIgG, elevated
|
Samples
|
4/30 (13.3%)
|
5/69 (7.2%)
|
n.s.
|
QIgG, if elevated
|
Ratio
|
4.7 (2.3-6; 4)
|
4.5 (2.4-7; 5)
|
n.s.
|
QAlb, all
|
Ratio
|
7.9 (3.2-32.7; 30)
|
5.7 (3-26.3; 74)
|
0.009
|
QAlb, elevated
|
Samples
|
20/30 (66.7%)
|
29/74 (39.2%)
|
0.017
|
QAlb, if elevated
|
Ratio
|
10.8 (6.5-32.7; 20)
|
8.3 (5.5-26.3; 29)
|
0.014
|
CSF TP, all
|
mg/dl
|
55.1 (20.5-176; 31)
|
41.4 (20.4-171.8; 77)
|
0.026
|
CSF TP, elevated
|
Samples
|
18/31 (58.1%)
|
31/77 (40.3%)
|
n.s.
|
CSF TP, if elevated
|
mg/dl
|
79 (46.7-176; 18)
|
62 (45.3-171.8; 31)
|
0.021
|
CSF TP, > 100 mg/dl
|
Samples
|
6/30 (20%)
|
3/85 (3.5%)
|
0.009
|
CSF l-lactate, all
|
mmol/l
|
2 (1.4-4.4; 22)
|
1.8 (1.1_4; 56)
|
n.s.
|
CSF l-lactate, elevated
|
Samples
|
9/22 (40.9%)
|
16/56 (28.6%)
|
n.s.
|
CSF l-lactate, if elevated
|
mmol/l
|
3.1 (2.3-4.4; 9)
|
2.6 (2.1-4; 16)
|
0.037
|
CSF l-lactate, > 3 mmol/l
|
Samples
|
6/25 (24%)
|
4/60 (6.7%)
|
n.s.
|
- Ratios and concentrations are given as median (with ranges and sample numbers in brackets)
- IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein; WCC white cell count