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Table 3 Effects of PLX and LPS on gene expression of markers of microglia/macrophages and proinflammatory cytokines. F values (F(1, 20)) from 2 (PLX diet vs. control diet) × 2 (LPS vs. control) ANOVA with 6 mice/group

From: Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats

Target molecule PLX LPS PLX) × LPS
Brain Cx3cr1 F(1, 20) = 684*** F(1, 20) = 5.29* F(1, 20) = 6.53*
Brain Itgam F(1, 20) = 333*** F(1, 20) = 9.61** F(1, 20) = 7.56*
Brain Il1b F(1, 20) = 1.43 NS F(1, 20) = 9.70** F(1, 20) = 1.22 NS
Brain Tnf F(1, 20) = 0.75 NS F(1, 20) = 21.1*** F(1, 20) = 0.95 NS
Brain Il6 F(1, 20) = 0.30 NS F(1, 20) = 7.56* F(1, 20) = 4.55*
Brain Il10 F(1, 20) = 1.10 NS F(1, 20) = 3.79+ F(1, 20) = 4.88*
Brain Oas1a F(1, 20) = 0.29 NS F(1, 20) = 14.7*** F(1, 20) = 0.31 NS
Liver Csf1r F(1, 20) = 23.9*** F(1, 20) = 12.3** F(1, 20) = 4.95*
Liver Itgam F(1, 20) = 3.22 NS F(1, 20) = 17.3*** F(1, 20) = 2.42 NS
Liver Il1b F(1, 20) = 0.41 F(1, 20) = 27.1*** F(1, 20) = 0.34
Liver Tnf F(1, 20) = 7.96** F(1, 20) = 39.1*** F(1, 20) = 7.86*
Liver Il6 F(1, 20) = 2.49 NS F(1,20) = 23.6*** F(1, 20) = 2.44 NS
Liver Il10 F(1,20) = 9.62** F(1, 20) = 15.2*** F(1, 20) = 9.18**
Liver Oas1a F(1, 20) = 4.15 NS F(1, 20) = 28.9*** F(1, 20) = 4.53*
  1. NS non-significant
  2. +p < 0.10, *p < 0.05, **p < 0.01, ***p < 0.001