Fig. 2
From: Age-dependent involvement of gut mast cells and histamine in post-stroke inflammation
Elevated levels of histamine following ischemic stroke in a blood plasma of young (Yg) and aged (Ag) mice at 6 and 24-h post-stroke compared to age matched controls. b Histamine levels of brain quantified by mass spectrometry in aged (Ag) mice at 6 and 24-h post-stroke compared to age-matched sham control mice. n = 3 (sham) and 5 (stroke) per group. Data are expressed as mean ± SEM (a) and median ± range (b), as well as individual values. *P < 0.05, **P < 0.01, ***P < 0.001. P values were calculated using one-way analysis of variance with Tukey multiple comparisons correction (a) and Kruskal-Wallis test with Dunn’s multiple comparison (b)