Fig. 7

Compositional differences in gut microbiota by 16S rRNA sequencing and qPCR of intestinal luminal content. a Visualization of beta-diversity, or between-samples diversity, with weighted UniFrac distances by principal coordinate analysis (PCoA) shows a clustering effect by strain between aged mice at 24-h post-stroke compared to age-matched sham controls and b corresponding family level bacterial distribution. c Visualization of beta-diversity, or between-samples diversity, with weighted UniFrac distances by principal coordinate analysis (PCoA) shows a clustering effect by strain between aged mice at 7-days post-stroke compared to age-matched sham controls and d corresponding order level bacterial distribution. n = 3 sham and n = 5 stroke (a and b); n = 5 sham and n = 5 stroke (c and d)