Fig. 4

Short-term outcome studies at 72 h after ICH. a Garcia test, b forelimb placement test, and c corner turn test at 72 h showed that neurological function was significantly impaired after ICH, and OXA treatment significantly improved outcomes. Kruskal-Wallis test with the Bonferroni correction, *p < 0.05 vs. sham group, #p < 0.05 vs. vehicle group. Error bars represent the means ± SD, n = 6 per group. d Brain water content was evaluated 72 h after ICH. There was no significant difference in brain edema in the contralateral brain hemisphere or the cerebellum. Brain edema increased in the ipsilateral hemisphere observed after ICH, which was significantly ameliorated with OXA administration. One-way ANOVA, *p < 0.05 vs. sham group, #p < 0.05 vs. vehicle group. Error bars represent mean ± SD, n = 6 per group. BG, basal ganglia; CX, cortex; Cerebel, cerebellum