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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats

Fig. 7

Proposed mechanism for CX3CR1-microglia and fractalkine during hypertension triggered by fructose in the NTS. Treatment with a CX3CR1 inhibitor (AZD8797) illustrated that CX3CR1-microglia acts as regulator of blood pressure through the ERK1/2-Akt-nNOS pathway. Inhibition of CX3CR1 decreases blood pressure and enhances the activity of Akt-ERK1/2-nNOS pathway in the NTS during fructose-induced hypertension

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Journal of Neuroinflammation

ISSN: 1742-2094