|
mRNA expression
|
Control
|
Ethanol
|
Ethanol + INCB3344
|
Control + INCB3344
|
|---|
|
BLBP
|
2.3E− 1 ± 9.4E− 3
|
3.3E− 1 ± 2.2E− 2*
|
2.5E− 1 ± 1.9E− 2
|
2.3E− 1 ± 6.4E− 3
|
|
CCL2
|
1.3E− 3 ± 4.9E− 5
|
2.0E− 3 ± 1.5E− 4*
|
1.4E− 3 ± 6.9E− 5
|
1.2E− 3 ± 5.2E− 5
|
|
CCR2
|
4.5E− 1 ± 3.4E− 3
|
6.7E− 3 ± 5.4E− 4*
|
4.8E− 3 ± 4.1E− 4
|
4.1E− 3 ± 4.8E− 4
|
- Maternal ethanol administration group (2 g/kg/day, E10–E15) with and without INCB3344 treatment (1 mg/kg/day, i.p.) was compared to Untreated and isocaloric Control groups of embryos at E19. Data are expressed as an averaged ratio (target gene expression/house-keeping gene expression) in each group and presented as mean ± SEM (n = 7/group, *p < 0.05 versus Control, Ethanol + INCB3344, and Control + INCB3344 groups). Difference between groups was analyzed using one-way ANOVA followed by SDS post hoc test
- BLBP brain lipid-binding protein, NEP neuroepithelium
