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Table 1 Parameters of the VehicleM and MCC950 groups at baseline and during post-cardiac arrest care after ROSC

From: NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury

Parameters Time points VehicleM MCC950
Body weight, g Baseline 377 ± 18 384 ± 20
Time from asphyxia to cardiac arrest, s Baseline 214.0 ± 21 210.9 ± 17
Time required for ROSC, s Baseline 90.77 ± 24 93.78 ± 27
Total dose of epinephrine, μg Baseline 13.2 ± 3.1 12.0 ± 3.4
Mean arterial pressure, mmHg Baseline 122 ± 8 120 ± 11
10 min 113 ± 7 110 ± 9
30 min 88 ± 10 91 ± 7
60 min 85 ± 7 81 ± 9
Heart rate, beats/min Baseline 400 ± 11 399 ± 9
10 min 419 ± 17 424 ± 20
30 min 364 ± 17 370 ± 16
60 min 375 ± 14 380 ± 9
Rectal temperature, °C Baseline 37.1 ± 0.3 37.0 ± 0.2
10 min 37.1 ± 0.2 36.8 ± 0.3
30 min 37.0 ± 0.3 36.9 ± 0.2
60 min 37.0 ± 0.2 36.9 ± 0.3
  1. Physiological variables are measured at baseline and at 10, 30, and 60 min after ROSC. The values are expressed as mean ± SD. VehicleM vehicle of MCC950