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Table 2 Parameters of the of the VehicleA and Ac-YVAD-cmk groups at baseline and during post-cardiac arrest care after ROSC

From: NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury

Parameters Time points VehicleA Ac-YVAD-cmk
Body weight, g Baseline 381 ± 13 374 ± 17
Time from asphyxia to cardiac arrest, s Baseline 220.4 ± 15 217.1 ± 23
Time required for ROSC, s Baseline 99.06 ± 17 96.45 ± 22
Total dose of epinephrine, μg Baseline 12.3 ± 3.1 11.1 ± 3.0
Mean arterial pressure, mmHg Baseline 119 ± 7 124 ± 11
10 min 116 ± 12 107 ± 7
30 min 84 ± 9 83 ± 5
60 min 80 ± 5 81 ± 11
Heart rate, beats/min Baseline 407 ± 11 403 ± 7
10 min 431 ± 15 427 ± 19
30 min 372 ± 11 369 ± 17
60 min 383 ± 17 379 ± 15
Rectal temperature, °C Baseline 36.8 ± 0.4 36.9 ± 0.2
10 min 37.1 ± 0.3 36.9 ± 0.3
30 min 37.0 ± 0.2 36.8 ± 0.3
60 min 36.8 ± 0.2 36.9 ± 0.2
  1. Physiological variables are measured at baseline and at 10, 30, and 60 min after ROSC. The values are expressed as mean ± SD. VehicleA vehicle of Ac-YVAD-cmk