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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Inhibition of leucine-rich repeats and calponin homology domain containing 1 accelerates microglia-mediated neuroinflammation in a rat traumatic spinal cord injury model

Fig. 5

LRCH1 knockdown promotes priming-induced activation of p38 MAPK and JNK signaling. a Representative Immunoblotting images showing the phosphorylation of p-38 MAPK (30 min after priming), Erk1/2 phosphorylation (15 min after priming), and JNK (30 min after priming) in microglia. b Statistics for the phosphorylation levels (phosphorylated protein of interest: total protein of interest) of each signaling molecule in microglia with or without priming. LC, microglia infected with control lentivirus. LL, microglia infected with LRCH1 shRNA-encoding lentivirus. *p < 0.05

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