Fig. 5
From: Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching
TM ameliorated the proinflammatory features of injured nerves. a Immunohistochemical staining of transverse nerve sections from Sprague-Dawley rats. Nerve sections from TM-treated nerves demonstrated an apparent reduction in IL-6 expression in comparison with that of nerves treated with PBS. n = 5. b Quantification of TNF-α, IL-1β, and IL-6 levels. c A concomitant increase in IL-10 was detected in nerve sections from the TM group. n = 5. d Quantification of IL-10 level. Scale bar, 20 μm. Mean ± SD. *p < 0.05 compared with the PBS group