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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

Fig. 2

Meta-analysis shows distinct acute injury and chronic neurodegeneration signatures, and a common pan-injury signature. a Flow-chart shows the criteria used to develop acute injury (AI), chronic neurodegenerative diseases (ND), and pan-injury (PAN) signatures. b Venn diagrams show the number of upregulated (UP) and downregulated (DOWN) genes for each of the signatures. c Heatmaps depict log2(fold change) of upregulated (UP) and downregulated (DOWN) genes comprising the three signatures

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