Fig. 1
From: CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation
Myelin internalization increases CD36 abundance in phagocytes in vitro. a mRNA expression of Cd36 in bone marrow-derived macrophages (BMDMs, n = 10 wells) and microglia (n = 6 wells) treated with myelin or left untreated for 24 h. b Flow cytometric analysis of surface CD36 abundance on BMDMs (n = 5 wells) and microglia (n = 8 wells) treated with myelin or left untreated for 24 h. c, d Quantification (fluorescence intensity) and representative images of CD36 abundance in BMDMs (n = 80 cells) and microglia (n = 80 cells) treated with myelin or left untreated for 24 h. Scale bar, 40 μm. MFI, mean fluorescence intensity; AU, arbitrary units. Data are represented as mean ± s.e.m. **p < 0.01 and ***p < 0.001