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Table 2 Fractional anisotropy in regions of interest (ROIs) that showed HIV effects

From: Microstructural brain abnormalities in HIV+ individuals with or without chronic marijuana use

Brain region Subject group 2-way ANCOVA main effect
Co-variate HIV MJ
SN SN + MJ HIV HIV + MJ Age % Recent regular alcohol use % Lifetime tobacco smokers
ALIC_L 0.47 ± 0.004 0.469 ± 0.004 0.455 ± 0.004 0.454 ± 0.004 0.014 0.472 0.965 0.001* 0.890
ALIC_R 0.466 ± 0.004 0.47 ± 0.005 0.455 ± 0.005 0.459 ± 0.005 0.031 0.296 0.708 0.028 0.508
CGC_L 0.382 ± 0.003 0.385 ± 0.004 0.374 ± 0.003 0.377 ± 0.003 0.009 0.243 0.610 0.038 0.493
CGH_L 0.368 ± 0.003 0.367 ± 0.003 0.363 ± 0.003 0.362 ± 0.003 0.077 0.434 0.987 0.099 0.630
PTR_R 0.455 ± 0.004 0.457 ± 0.005 0.447 ± 0.005 0.448 ± 0.005 0.002 0.357 0.076 0.094 0.797
SFO_L 0.406 ± 0.004 0.404 ± 0.005 0.394 ± 0.005 0.392 ± 0.005 0.041 0.360 0.680 0.018 0.749
SFO_R 0.418 ± 0.004 0.416 ± 0.005 0.408 ± 0.004 0.406 ± 0.005 0.005 0.237 0.817 0.054 0.657
SS_R 0.412 ± 0.003 0.413 ± 0.003 0.403 ± 0.003 0.404 ± 0.003 0.000 0.443 0.550 0.020 0.804
Caudate_L 0.357 ± 0.003 0.361 ± 0.003 0.35 ± 0.003 0.355 ± 0.003 0.066 0.659 0.007 0.065 0.215
  1. All uncorrected p values < 0.05 from two-way ANCOVA are shown; the other 11 ROIs not listed showed no HIV or MJ effects. No HIV-by-MJ interaction was found for FA measurement in any of the ROIs. Bold: uncorrected p value < 0.05 for HIV or MJ main effects or their interaction
  2. ALIC anterior limb of the internal capsule, CGC cingulum, cingulate gyrus part, CGH cingulum, hippocampal part, PTR posterior thalamic radiation, PLIC posterior limb of the internal capsule, SS sagittal stratum, SFO superior fronto-occipital fasciculus, R right, L left, HIV HIV seropositive, SN HIV seronegative, MJ marijuana
  3. *p values remained significant after Holm correction for multiple comparisons