Fig. 2
Effects of FMT in antibiotic-treated and water-treated mice. a Body weight (repeated measure two-way ANOVA, antibiotic: F1,24 = 38.007, P < 0.001; FMT: F1,24 = 0.667, P = 0.422; interaction: F1,24 = 2.282, P = 0.144). b SPT (two-way ANOVA, antibiotic: F1,24 = 1.021, P = 0.322; FMT: F1,24 = 3.722, P = 0.066; interaction: F1,24 = 9.757, P = 0.005). c Plasma IL-6 (two-way ANOVA, antibiotic: F1,24 = 13.300, P = 0.001; FMT: F1,24 = 10.919, P = 0.003; interaction: F1,24 = 11.393, P = 0.003). d GluA1 (two-way ANOVA, antibiotic: F1,24 = 3.833, P = 0.062; FMT: F1,24 = 6.437, P = 0.018; interaction: F1,24 = 11.657, P = 0.002). e PSD-95 (two-way ANOVA, antibiotics: F1,24 = 0.014, P = 0.908; FMT: F1,24 = 15.604, P = 0.001; interaction: F1,24 = 3.284, P = 0.082). f PCoA analysis of gut microbiota data. Data are shown as mean ± S.E.M. (n = 7). *P < 0.05, **P < 0.01, ***P < 0.001. FMT fecal microbiota transplantation, NS not significant, W + FMT-C water + FMT from control (no CSDS) mice, W + FMT-S water + FMT from CSDS-susceptible mice, A + FMT-S antibiotic + FMT from CSDS-susceptible mice, A + FMT-C antibiotic + FMT from control (no CSDS) mice