Fig. 1
From: Serum amyloid A inhibits astrocyte migration via activating p38 MAPK
Upregulation of Saa3 in the cortex and hippocampus of APP/PS1 transgenic mice. a Serial sections of 12-month-old WT, APP/PS1, and Saa3−/− mouse brain were stained for Saa3 protein using a rabbit anti-Saa3 polyclonal antibody and Alexa Fluor 488-conjugated anti-rabbit IgG (green fluorescence). The cell nuclei were stained with DAPI (blue). The scale bar in the upper left panel is 150 μm. b Quantification of the Saa3 fluorescence was shown. Results are expressed as the mean ± SEM based on four individual fields for each region, using 3–4 mice in each group. *p < 0.05; **p < 0.01; ***p < 0.001 compared with WT mice