Fig. 3
From: Serum amyloid A inhibits astrocyte migration via activating p38 MAPK
SAA inhibits astrocyte migration in Boyden chamber assay. Primary cultures of astrocytes and U251 cells were treated for 12 h with SAA (0.1–1 μM) or LPS (2.5 ng/mL). The cell migration was examined using 48-well chemotaxis chambers. Representative images of migrated cells (primary astrocytes and U251 cells) on membrane filters were shown in a, and quantified data were shown in b and c. Magnification, × 400. Results are expressed as the mean ± SEM based on three independent experiments, each with three wells for each group. *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control (DMEM)