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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Rh-relaxin-2 attenuates degranulation of mast cells by inhibiting NF-κB through PI3K-AKT/TNFAIP3 pathway in an experimental germinal matrix hemorrhage rat model

Fig. 6

LY294002 significantly decreased PI3K (a, d, l), phosphorylated Akt (a, e), and TNFAIP3 (a, f) expression, which was accompanied by the increase of phosphorylated NF-κB (a, g), chymase (a, h), tryptase (a, i), IL-6 (a, j), and TNF-α (a, k) on the first day after GMH. *P < 0.05, Sham vs. LY294002; #P > 0.05, GMH + vehicle vs. LY294002; $P < 0.05, DMSO vs. LY294002, one-way ANOVA, Tukey’s test, n = 6

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Journal of Neuroinflammation

ISSN: 1742-2094