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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment

Fig. 4

Effect of CRID3 on M1 and M2 cells in the injured spinal cord as distinguished by IHF. (a-f) Representative images of CD68 (green) and CCR7 (red) (a-c) or Arg1 (e-f) expression in the spinal cords in sham, SCI (vehicle), and SCI (CRID3) groups. Cells were counterstained with Hoechst 33342 (blue) to visualize nuclei. (g and h) Quantitative analysis of CD68+CCR7+ (g) and CD68+Arg1+ (h) cells in the indicated groups. Data represent the mean ± SD (n = 6). *P < 0.05, **P < 0.01 (non-parametric Kruskal-Wallis ANOVA, followed by individual Mann-Whitney U tests)

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Journal of Neuroinflammation

ISSN: 1742-2094