Fig. 5

Onset of neurodegenerative changes in cerebellum of Smox/Sat1-dKO mice. FJC staining reveals the presence of increased neurodegeneration (green fluorescence) as early as 8 weeks (white arrows) in Purkinje cell layer and axonal staining in the white matter (orange arrows) of the cerebellum of Smox/Sat1-dKO mice