Fig. 8
Tan IIA suppresses RAGE/NF-κB signaling pathway activation in Aβ1–42-stimulated BV2 and U87 cells. a Western blotting and densitometry analysis of RAGE, phospho-IκBα, total-IκBα, and total-NF-κB p65 (cytoplasm and nucleus) in BV2 cells. b Western blotting and densitometry analysis of RAGE, phospho-IκBα, total-IκBα, and total-NF-κB p65 (cytoplasm and nucleus) in U87 cells. c Immunofluorescence for NF-κB p65 (green) and DAPI (blue) in BV2 cells. Scale bar = 50 μm. d Immunofluorescence for NF-κB p65 (red) and DAPI (blue) in U87 cells. Scale bar = 50 μm. n = 5. Data were presented as mean ± SD. #p < 0.05 or ##p < 0.01 vs. control, and *p < 0.05 or **p < 0.01 vs. Aβ1–42 treated cells