Table 1 Clinical characteristics of patients with and without post-stroke cognitive impairment

Age, year

61.1 (7.1)

68.4 (9.4)

< 0.01

Education, year

10.4 (3.1)

7.5 (4.6)

< 0.01

Male, No. (%)

31 (82)

16 (64)

0.12

APOE ε4 carrier, No. (%)

4 (11)

3 (12)

1.00^a

Days between stroke onset and cognition evaluation

102.4 (29.7)

101.6 (21.0)

0.91

Days between stroke onset and ¹⁸F-THK-5351 scanning

92.8 (14.8)

104.4 (24.4)

0.04

Days between stroke onset and ¹⁸F-florbetapir scanning

100.4 (31.6)

101.2 (28.4)

0.92

 Hypertension, No. (%)

31 (82)

24 (96)

0.13^a

 Diabetes mellitus, No. (%)

14 (37)

6 (24)

0.28

 Dyslipidemia, No. (%)

32 (84)

17 (68)

0.13

 Gout, No. (%)

7 (18)

3 (12)

0.72^a

 PVL score

0.4 (0.8)

0.8 (1.1)

0.13

 DWML score

2.6 (1.3)

3.2 (1.2)

0.08

 Enlarged perivascular space, No. (%)

11 (29)

8 (32)

0.80

 Lobar microbleed, No. (%)

6 (16)

6 (24)

0.52^a

 Deep microbleed, No. (%)

6 (16)

2 (8)

0.46^a

 Lacune, No. (%)

10 (26)

4 (16)

0.34

 NIHSS

1.5 (1.3)

2.4 (2.3)

0.06

 Ischemic stroke, No. (%)

35 (92)

23 (92)

1.00^a

 Left hemisphere stroke, No. (%)

17 (45)

15 (60)

0.24

 Supratentorial stroke lesion, No. (%)

35 (92)

23 (92)

1.00^a

 Stroke volume, %

3.39E-6 (4.45E-6)

6.18E-6 (6.57E-6)

0.07

MTA score

0.8 (1.0)

1.3 (1.3)

0.09

Cortical thickness, mm

2.44 (0.08)

2.37 (0.10)

0.01

 Total Z-SUM-2, Z > 2

86763 (96363)

136773 (126302)

0.09

 Total Z-SUM-3, Z > 3

43536 (58763)

82344 (82885)

0.03

 Total Z-SUM-4, Z > 4

25822 (40406)

50558 (53591)

0.04

 Total Z-SUM-5, Z > 5

17404 (31432)

31059 (34631)

0.11