Fig. 1From: The peri-menopause in a woman’s life: a systemic inflammatory phase that enables later neurodegenerative diseaseAt the reproductive senescence/menopausal transition the ovarian failure is associated with release of extracellular vesicles containing inflammasomes, which may be responsible for low-grade systemic inflammation. This low-grade inflammation may compromise the blood-brain barrier (BBB), making the brain more susceptible to inflammation and neurodegenerative diseasesBack to article page