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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: The peri-menopause in a woman’s life: a systemic inflammatory phase that enables later neurodegenerative disease

Fig. 1

At the reproductive senescence/menopausal transition the ovarian failure is associated with release of extracellular vesicles containing inflammasomes, which may be responsible for low-grade systemic inflammation. This low-grade inflammation may compromise the blood-brain barrier (BBB), making the brain more susceptible to inflammation and neurodegenerative diseases

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