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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Corticosteroid receptor rebalancing alleviates critical illness-related corticosteroid insufficiency after traumatic brain injury by promoting paraventricular nuclear cell survival via Akt/CREB/BDNF signaling

Fig. 2

Effects of MP and CORT on the expression of CRH and the number of CRH- and TUNEL-positive cells in the ipsilateral hippocampus after TBI. a Representative images of CRH- (red, white arrow) and TUNEL-(green, yellow arrow) positive cells in the PVN. b Quantification of CRH-positive cells in the PVN. c Quantification of TUNEL-positive cells in the PVN. d Representative western blot images showing CRH expression. e Quantification of CRH expression. The relative band density was measured with ImageJ (1.49 V) and normalized to that of β-actin, and the percent expression compared to that of the sham controls was calculated for each sample. *P < 0.05 compared to the sham group; #P < 0.05 compared to the CCI control group. The data are presented as the means ± SD of 6 animals per group

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Journal of Neuroinflammation

ISSN: 1742-2094