Fig. 2

Electrostimulation of the CSN increases breath rate and decreases arterial blood pressure in mice. Eight to 10-week-old C57BL/6 mice were obtained, and CSN isolation surgery was performed. a Breath rate was recorded for 5 min, and the average breath per minute was calculated at baseline, during stimulation (200 μA, 5 Hz) and immediately after stimulation. Breath rate in mice before, during and after stimulation. Each individual point represents an animal, and data is expressed as means ± SD. b The mean carotid pressure recorded in anaesthetised mice (n = 3) before and during CSN electrostimulation with either 1 mA (left), 600 μA (middle) or 200 μA (right) current amplitude. Traces are averaged values