Fig. 6
From: Immunological classification of gliomas based on immunogenomic profiling
Molecular and genomic features associated with the glioma immune subtypes in TCGA-glioma. a Immunity-high has significantly higher tumor mutation burden (TMB) and neoantigens than immunity-low gliomas. b More frequent arm-level somatic copy number alterations in immunity-high versus immunity-low gliomas. The red asterisks indicate the chromosome arms in which immunity-high gliomas are more frequently amplified or deleted than immunity-low gliomas. c Lower intratumor heterogeneity scores in immunity-high than in immunity-low gliomas. The intratumor heterogeneity scores were evaluated by the MATH algorithm [23]. d Seventy-two genes more frequently mutated in immunity-high than in immunity-low gliomas