Fig. 5

Smaller lesion sizes in CCL3^−/− mice at day 28 after SCI. a Representative images of GFAP immunoreactivity (green) and myelin content (red), in laminectomy controls, wild-type, and CCL3^–/– mice at day 28 after SCI. Scale bars 200 μm. b Quantitative analysis revealing significantly smaller lesion sizes at the epicenter in CCL3^−/− compared to wild-type mice. c No difference was detected in the myelin content at the lesion epicenter between groups. d Quantitative analysis revealing significantly smaller lesion proportions in CCL3^−/− compared to wild-type mice, starting at 112 μm rostral and caudal from the epicenter. e Quantitative analysis revealing no difference between groups in the number of astrocytes adjacent to the lesion epicenter. f Representative images of CSPG immunoreactivity (green) and DAPI (blue). Scale bars 40 μm. g Quantitative analysis shows no difference between groups in the amount of CSPG deposits at day 28 post-SCI. n = 6 wild-type, 5 CCL3^−/−. Data points represent mean ± SEM. * < p value 0.05