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Fig. 11 | Journal of Neuroinflammation

Fig. 11

From: Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis

Fig. 11

Impact of miRNA-27a inhibitor on isoliquiritin-generated antidepressant and anxiolytic efficacy in CSDS mice. a Schematic timeline of the experimental procedure. b Sucrose preference test (n = 13 per group). c Tail suspension test (n = 10 per group). d Forced swimming test (n = 10 per group). e, f Social interaction test (n = 8 per group). Data are presented as mean ± SEM. ##p < 0.01, compared to blank group; **p < 0.01, compared to CSDS group; &p < 0.05, &&p < 0.01, compared to CSDS+ isoliquiritin group

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