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Fig. 12 | Journal of Neuroinflammation

Fig. 12

From: Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis

Fig. 12

Impact of miRNA-27a inhibitor on isoliquiritin-generated deactivation of pyroptosis signaling in the hippocampus of CSDS mice. a mRNA expression level of miRNA-27a. b Representative Western blots. c–e Protein levels of SYK, p-NF-κB, and GSDMD-N. Data are presented as mean ± SEM (n = 3 per group). ##p < 0.01, compared to blank group; *p < 0.05, **p < 0.01, compared to CSDS group; &p < 0.05, &&p < 0.01, compared to CSDS+ isoliquiritin group

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Journal of Neuroinflammation

ISSN: 1742-2094