Fig. 4
From: Analysis of ALS-related proteins during herpes simplex virus-2 latent infection
Differential expression of MHC-II in microglia during HSV-2esi latent infection. a Z-stack confocal images of Mock (n = 4) and HSV-2esi (n = 5) SCs from two independent experiments. MHC-II in green, Iba1 in red, NeuN in white, and Dapi in blue. Open yellow arrowhead point to a MHC-IIhigh cell in the white matter; solid red arrowhead point to a MHC-IIhigh cell in the gray matter. b Z-stack confocal images of HSV-2es SCs on lamina IX. MHC-II in green, Iba1 in red, NeuN in white, and Dapi in blue. Red arrowhead points to a MHC-IIhigh cell close to motor neurons. c Z-stack confocal images of HSV-2es SCs. MHC-II in green, Iba1 in red, NeuN in white, and Dapi in blue. Green arrowhead point to a high-expressing MHC-II cell, magenta arrowhead point to a moderate-expressing MHC-II cell, and red arrowhead point to a low-expressing MHC-II cell