Fig. 1

Effect of L-NAME on seizure activity in response to pilocarpine. As compared to vehicle, L-NAME does not affect total EEG power, the latency of SE on-set and behavioral seizure severity (seizure score) in response to pilocarpine. (a) Representative EEG (upper panels) and frequency-power spectral temporal maps (lower panels) in response to pilocarpine (n = 7, respectively). (b-d) Quantification of total EEG power (B), the latency of SE on-set (c) and behavioral seizure severity (d) in response to pilocarpine (n = 7, respectively). Open circles indicate each individual value. Horizontal bars indicate mean value. Error bars indicate S.E.M