Fig. 8
From: Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8
Blockage of MFG-E8 on the expression of AMPK and Src in microglia treated with propofol. BV2 cells were treated with or without an MFG-E8 antibody (5 μg/ml)/IgG antibody (5 μg/ml) for 45 min after treatment with propofol (12.5 μM) for 4 h. The expression of p-AMPK, AMPK, p-Src, Src, and GAPDH was measured by western blotting (a). The bands were quantitatively analyzed (b, c, d, e). The data are presented as the mean ± SD. Pro, propofol; M8 Ab, MFG-E8-neutralizing antibody. *P < 0.05 versus the control