Fig. 10

Intrathecal administration of LRU and MIP decreased pNF-κB-p65 protein expression in rat DRG after EM. a LRU or Vehicle was delivered intrathecally daily for three consecutive days from POD3. The representative protein bands of pNF-κB-p65 in DRG from sham rats, EM 14d + LRU rats and EM 14d + Vehicle rats. b LRU downregulated the expression of pNF-κB-p65 protein in the DRG induced by EM. n = 4, *p < 0.05, EM 14d + vehicle versus sham; ^#p < 0.05, EM 14d + LRU versus EM 14d + vehicle, one-way ANOVA followed by Bonferroni’s post hoc test. c MIP or control peptide was delivered intrathecally daily for three consecutive days from POD3. The representative protein bands of pNF-κB-p65 in DRG from sham rats, EM 14d + MIP rats, and EM 14d + control rats. d MIP downregulated the expression of pNF-κB-p65 protein in the DRG induced by EM. n = 4, *p < 0.05, EM 14d + control versus sham and EM 14d + MIP versus sham; ^#p < 0.05, EM 14d + MIP versus EM 14d + control, one-way ANOVA followed by Bonferroni’s post hoc test