Fig. 2

Neurological outcomes and blood brain barrier permeability after subarachnoid hemorrhage in CypA^−/− mice. a Modified Garcia test results of each group at 24 h after SAH. b Beam balance test results of each group at 24 h after SAH. c Evans blue fluorescence evaluation. d extravasation at 24 h after SAH. e Cadaverine-Alexa Flour 555 fluorescence evaluation. f Fluorescent efficiency at 24 h after SAH. g Representative immunohistochemistry staining slices of Collagen IV (Green) and Lectin (White) at 24 h after SAH. n = 6 for each group @: vs. flox/flox + sham P < 0.05, #: vs. flox/flox + SAH P < 0.05, &: vs. KO + sham, P < 0.05. Arrow indicates the breakdown of continuous endothelia cell layer