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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Cyclophilin a signaling induces pericyte-associated blood-brain barrier disruption after subarachnoid hemorrhage

Fig. 8

Effects of exogenous CypA and CD147 small interfering RNA treatment on blood–brain barrier after subarachnoid hemorrhage. a, b Representative Western blot bands and quantitative analysis of the inhibition effect of CD147 siRNA after SAH. c Modified Garcia test and d beam balance test results of each group at 24 h after SAH. e Brain water content assessment at 24 h after SAH. f Evans blue extravasation evaluation at 24 h after SAH. g Representative immunohistochemistry staining slices Collagen IV (Green) and Lectin (White) at 24 h after SAH. @: vs. sham P < 0.05, #: vs. SAH + vehicle P < 0.05 and $: vs. SAH + CypA + Scr siRNA P < 0.05

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