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Table 2 Comparison of cytokines among patients with unipolar depression taking different types of antidepressant

From: A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder

 

SSRI (n = 19)

SNRI (n = 18)

NDRI (n = 11)

NaSSA (n = 4)

Agomelatine (n = 9)

Significance

C-reactive protein (CRP) (pg/ml)

2322.6 ± 3028.6

999.8 ± 1408.8

3133.2 ± 2206.4

978.3 ± 605.4

1366.4 ± 1930.0

n.s.

Soluble interleukin-2 receptor (sIL-2R) (pg/ml)

643.7 ± 211.2

611.5 ± 177.7

851.0 ± 358.3

825.1 ± 316.8

561.7 ± 220.8

n.s.

Soluble interleukin-6 receptor (sIL-6R) (pg/ml)

29,504.2 ± 5970.7

28,075.4 ± 9047.5

29,518.2 ± 9497.3

35,502.9 ± 8097.8

28,205.8 ± 11,328.8

n.s.

Soluble tumor necrosis factor receptor type 1 (sTNF-R1) (pg/ml)

774.7 ± 134.7

753.1 ± 147.2

779.0 ± 235.0

863.9 ± 583.3

653.0 ± 181.7

n.s.

  1. NaSSA noradrenergic and specific serotonergic antidepressant, NDRI norepinephrine dopamine reuptake inhibitor, SNRI serotonin-norepinephrine reuptake inhibitor, SSRI selective serotonin reuptake inhibitor, n.s. not significant