A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder

Table 4 Gray matter volume differences between bipolar disorder (BD) and unipolar depression (UD) ^a

Index	Harvard-Oxford Cortical Structural Atlas	x	y	z	Cluster size	T value	P value (FDR corr.)
BD > UD
		–	–	–	–	–	–
UD > BD
1	R. cerebellar lobule VIII	20	− 58	− 50	15,271	8.15	< 0.001**
2	R. putamen	29	− 3	− 2	3835	5.92	< 0.001**
3	L. putamen	− 26	− 3	− 1	3437	5.82	< 0.001**
4	R. superior frontal gyrus	25	53	− 5	801	4.43	0.001*
5	Left lingual gyrus	− 27	− 91	− 13	679	4.34	0.001*
6	L. precentral gyrus	− 48	6	29	543	4.26	0.001*
7	R. fusiform gyrus	32	− 48	− 6	290	4.25	0.001*
8	L. calcarine	− 13	− 77	7	216	4.19	0.001*
9	R. precuneus	1	− 63	53	258	4.19	0.001*
10	L. inferior temporal gyrus	− 44	− 14	− 31	355	4.13	0.001*
11	L. hippocampus	− 25	− 14	− 23	143	4.09	0.001*
12	L. superior frontal gyrus	− 17	56	− 12	238	3.93	0.002*

^aAdjusted for age, sex, BMI, duration of illness, and total intracranial volume (TIV)

ISSN: 1742-2094