Fig. 6

CXCR2 in neutrophils contributes to the proinflammatory phenotype during EAE. a Percentage of ROS⁺ neutrophils isolated from spleens and lymph nodes of control naïve mice, control EAE mice, and Cxcr2 cKO mice. b Percentage of ROS⁺ neutrophils isolated from peritoneal space of thioglycolate-injected wild-type mice post-treatment with rCXCL1 at 10 or 30 ng/ml or LPS at 100 ng/ml as positive control. c Gene transcription levels of Ncf, Mpo, Il1b and Tnfa in neutrophils isolated from spleens and lymph nodes. *p < 0.05, two-tailed unpaired Student’s t test