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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats

Fig. 5

INT777 suppresses neuroinflammation induced by middle cerebral artery occlusion (MCAO). a–c Representative western blot images and quantitative analysis of cleaved caspase-8 and NLRP3 bands. d Effects of INT777 on levels of TNF-α, IL-1β, and IL-18 in brain tissue. n = 6 per group. *P < 0.05 vs. Sham, #P < 0.05 vs. MCAO + vehicle

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Journal of Neuroinflammation

ISSN: 1742-2094