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Table 1 Properties of Ca2+ transients evoked in human microglial cells under different experimental conditions

From: ATP-evoked intracellular Ca2+ transients shape the ionic permeability of human microglia from epileptic temporal cortex

Stimulus Resp. cells (%) Basal (R) Peak (R) ΔR T0-100 (s) T100-50 (s) [n]
ATP 100 (62/62) 0.22±0.01 0.36±0.02 0.142±0.002 114±8 419±24 [27]
ATP (LPS) 97.6 (41/42) 0.219±0.007 0.35±0.02 0.13±0.02 67±6 353±24 [28]
ATP Ca2+-free 65.2 (15/23) 0.177±0.007 0.191±0.008 0.014±0.004 336±29 Nd [15]
GSK 1702934A 61.6 (74/120) 0.42±0.01 0.48±0.02 0.059±0.004 42±3 441±19 [29]
Thapsigargin 28.4 (19/67) 0.33±0.03 0.37±0.04 0.039±0.004 47±6 307±34 [5]
  1. Amplitude and kinetic parameters of evoked Ca2+ transients were measured on a subset [n] of total responsive cells, in which it was possible to resolve the peak and the recovery of the Ca2+ signal. Data were obtained from 3, 2, 3, 2, and 2 different patients for ATP, ATP in LPS-treated cells, ATP in Ca2+-free, GSK 1702934A, and thapsigargin, respectively