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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice

Fig. 4

The effects of rCCL17 treatment on neuronal apoptosis and neuronal apoptotic molecular markers after ICH. a Representative images of the co-localization of TUNEL (red) with neurons (NeuN, green) and (b) FJC (green) staining in the perihematomal area at 72 h after ICH. c Brain sample with schematic illustration showing the area (indicated by white square) used for FJC and TUNEL positive cell counting in the perihematomal region. d Quantitative analyses of TUNEL and FJC-positive cells in the perihematomal area at 72 h after ICH (n=4/group). e, f Representative western blot bands and quantitative analyses of Bax and Bcl-2 protein levels at 72 h after ICH. *p<0.05 vs sham, @p<0.05 vs ICH + vehicle, mean ± SD, one-way ANOVA, Tukey test, n=6/group, scale bar=50 μm

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