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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer’s disease

Fig. 3

L-AAA treatment affects the neuroinflammatory profile in the cortex. Quantification of expression of a TNFα, b IL-6, c IL-4, d IL-1β, e IL-10, f TGF-β, g MCP1, and h MIP-1α by ELISA in conditioned media from OBCSs of WT and 5XFAD mice treated with L-AAA for 24 h (n=6–18). Values shown in graphs represent the mean value ± SEM. Statistical analysis included one-way ANOVA with Tukey’s multiple-comparison post-hoc test. *P<0.05; **P<0.01; ***P<0.001

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